Rapid ultra-performance liquid chromatography assay of losartan potassium in bulk and formulations
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چکیده
منابع مشابه
A rapid assay for angiotensin-converting enzyme activity using ultra-performance liquid chromatography-mass spectrometry.
Angiotensin-converting enzyme (ACE) plays an important role in the renin-angiotensin system and ACE activity is usually assayed in vitro by monitoring the transformation from a substrate to the product catalyzed by ACE. A rapid and sensitive analysis method or ACE activity by quantifying simultaneously the substrate hippuryl-histidyl-leucine and its product hippuric acid using an ultra-performa...
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A rapid and sensitive HPLC method was developed for determination of losartan in plasma. Losartan was extracted from plasma by a two-step extraction procedure using chloroform as extracting solvent in acidic medium. HPLC analysis was performed on a cyano reversed-phase column using phosphate buffer (pH 4.3), acetonitrile (750:250, v/v) as mobile phase with a flow rate of 0.9 mL/min. Sodium dicl...
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ERDAL DINÇ1*, EDA BÜKER1, DUMITRU BALEANU2, 1Ankara University, Faculty of Pharmacy, Department of Analytical Chemistry, 06100, Tandoðan-Ankara, Turkey 2 Department of Mathematics and Computer Sciences, Faculty of Arts and Sciences, Çankaya University, 06530 Ankara, Turkey 3 National Institute for Laser, Plasma and Radiation, Physics, Institute of Space Sciences, Magurele-Bucharest, P.O. Box, M...
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Michael E. Swartz, Ph.D. Principal Scientist, Waters Corporation, Milford, Massachusetts, e-mail [email protected]. igh performance liquid chromatography (HPLC) is a proven technique that has been used in laboratories worldwide over the past 30-plus years. One of the primary drivers for the growth of this technique has been the evolution of packing materials used to effect the separatio...
متن کاملAssay of Famotidine in Bulk and Formulations
A reverse phase liquid chromatographic method (RP-HPLC) was developed to estimate the amount of famotidine in bulk and its pharmaceutical formulations. WatersAlliance HPLC system equipped with auto sampler, ultra-violet detector and symmetry C8 (4.6mm ID x 150mm, 3.5 μm, Make: XTerra) column were used for the quantification of the drug. Separation was carried out by using potassium dihydrogen p...
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ژورنال
عنوان ژورنال: Journal of Analytical Science and Technology
سال: 2014
ISSN: 2093-3371
DOI: 10.1186/s40543-014-0033-2